锶在骨组织工程中的研究进展
Research progress on strontium in bone tissue engineering
作者：张佳, 柳忠豪
Author：Zhang Jia, Liu Zhonghao
收稿日期：2017-05-05 年卷（期）页码：2018,45(1):50-54
期刊名称：国际口腔医学杂志
Journal Name：International Journal of Stomatology
关键字：骨替代材料,锶,骨缺损,骨组织工程,
Key words：bone subsititute materials,strontium,bone defect,bone tissue engineering,
基金项目：
中文摘要
骨替代材料被广泛应用于骨缺损的修复过程,在其基础上掺入促进骨修复的材料或因子是如今骨替代材料研究的主要热点。锶离子作为体内的一种必需微量元素能够同时刺激新骨形成并减少骨质吸收。近年来,众多学者将锶离子掺入各类骨替代材料中发现,锶的掺入不仅能改善骨替代材料的物理、化学性能,而且可以改变细胞行为,提高体内成骨能力。本文就以上几个方面对掺锶骨替代材料的研究情况进行综述。
英文摘要
Bone substitute materials are widely used in the process of repairing bone defect, the addition of factors promoting bone regeneration is the main hot spots in the research of bone substitute materials. As a necessary trace element, strontium can simultaneously stimulate new bone formation and reduce bone absorptionin vivo. In recent years, many scholars combined strontium with all kinds of bone substitute materials, found that strontium can not only improve the physical and chemical properties of bone substitute materials, but also can change cell behavior, improve the abilities of osteogenesis. This article summarized the above aspects of strontium-doping bone substitute materials.
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